HEADER DEOXYRIBONUCLEIC ACID 26-JAN-93 ZDFS33 JRNL AUTH H.ZHANG, G.A.VAN DER MAREL, J.H.VAN BOOM, JRNL AUTH 2 A. H.-J.WANG JRNL TITL CONFORMATIONAL PERTURBATION OF THE ANTICANCER JRNL TITL 2 NUCLEOSIDE ARABINOSYLCYTOSINE ON Z-DNA: MOLECULAR JRNL TITL 3 STRUCTURE OF (ARAC-DG)3 AT 1.3 ANGSTROMS RESOLUTION JRNL REF BIOPOLYMERS V. 32 1559 1992 JRNL REFN ASTM BIPMAA US ISSN 0006-3525 0161 SEQRES 1 A 2 C G CRYST1 17.960 17.960 43.220 90.00 90.00 120.00 P 65 2 2 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.055679 0.032146 0.000000 0.00000 SCALE2 0.000000 0.064293 0.000000 0.00000 SCALE3 0.000000 0.000000 0.023137 0.00000 ATOM 1 P +C A 1 0.198 -7.746 -0.735 1.00 24.00 P ATOM 2 O1P +C A 1 -0.323 -7.279 -2.118 1.00 21.90 O ATOM 3 O2P +C A 1 -0.530 -9.130 -0.648 1.00 26.50 O ATOM 4 O5* +C A 1 -0.332 -6.890 0.519 1.00 22.80 O ATOM 5 C5* +C A 1 -0.117 -6.766 1.902 1.00 24.00 C ATOM 6 C4* +C A 1 -0.709 -5.459 2.420 1.00 23.80 C ATOM 7 O4* +C A 1 0.224 -4.651 3.155 1.00 23.30 O ATOM 8 C3* +C A 1 -1.374 -4.588 1.383 1.00 23.40 C ATOM 9 O3* +C A 1 -2.568 -3.982 2.075 1.00 24.30 O ATOM 10 C2* +C A 1 -0.377 -3.577 0.994 1.00 23.10 C ATOM 11 O2* +C A 1 0.431 -3.857 -0.130 1.00 23.40 O ATOM 12 C1* +C A 1 0.368 -3.469 2.334 1.00 23.10 C ATOM 13 N1 +C A 1 1.769 -3.126 2.118 1.00 22.60 N ATOM 14 C2 +C A 1 2.012 -1.742 2.031 1.00 22.80 C ATOM 15 O2 +C A 1 1.167 -0.871 2.075 1.00 22.20 O ATOM 16 N3 +C A 1 3.367 -1.447 1.902 1.00 22.50 N ATOM 17 C4 +C A 1 4.310 -2.333 1.815 1.00 22.50 C ATOM 18 N4 +C A 1 5.559 -1.913 1.772 1.00 23.30 N ATOM 19 C5 +C A 1 3.978 -3.686 1.902 1.00 22.80 C ATOM 20 C6 +C A 1 2.757 -4.028 2.075 1.00 22.70 C ATOM 21 P G A 2 1.042 -5.164 -5.921 1.00 27.60 P ATOM 22 O2P G A 2 1.563 -6.004 -7.002 1.00 30.50 O ATOM 23 O2P G A 2 -0.332 -4.837 -5.921 1.00 29.80 O ATOM 24 O5* G A 2 1.482 -6.299 -4.797 1.00 22.30 O ATOM 25 C5* G A 2 2.658 -5.942 -4.149 1.00 21.00 C ATOM 26 C4* G A 2 2.892 -6.875 -3.025 1.00 21.20 C ATOM 27 O4* G A 2 4.265 -6.766 -2.853 1.00 20.70 O ATOM 28 C3* G A 2 2.362 -6.641 -1.686 1.00 21.30 C ATOM 29 O3* G A 2 1.706 -7.839 -1.167 1.00 22.30 O ATOM 30 C2* G A 2 3.538 -6.439 -0.778 1.00 21.30 C ATOM 31 C1* G A 2 4.732 -6.486 -1.599 1.00 22.10 C ATOM 32 N9 G A 2 5.325 -5.179 -1.772 1.00 22.50 N ATOM 33 C8 G A 2 6.708 -4.962 -1.902 1.00 23.10 C ATOM 34 N7 G A 2 7.013 -3.655 -1.988 1.00 23.50 N ATOM 35 C5 G A 2 5.765 -3.017 -1.902 1.00 23.50 C ATOM 36 C6 G A 2 5.442 -1.649 -2.031 1.00 23.40 C ATOM 37 O6 G A 2 6.214 -0.747 -2.161 1.00 23.50 O ATOM 38 N1 G A 2 4.059 -1.369 -1.902 1.00 23.50 N ATOM 39 C2 G A 2 3.188 -2.349 -1.686 1.00 23.30 C ATOM 40 N2 G A 2 1.904 -1.991 -1.513 1.00 23.70 N ATOM 41 N3 G A 2 3.475 -3.655 -1.686 1.00 23.40 N ATOM 42 C4 G A 2 4.759 -3.951 -1.815 1.00 23.30 C TER 43 G A 2 ATOM 44 P +C B 1 0.198 7.746 0.735 1.00 24.00 P ATOM 45 O1P +C B 1 -0.323 7.279 2.118 1.00 21.90 O ATOM 46 O2P +C B 1 -0.530 9.130 0.648 1.00 26.50 O ATOM 47 O5* +C B 1 -0.332 6.890 -0.519 1.00 22.80 O ATOM 48 C5* +C B 1 -0.117 6.766 -1.902 1.00 24.00 C ATOM 49 C4* +C B 1 -0.709 5.459 -2.420 1.00 23.80 C ATOM 50 O4* +C B 1 0.224 4.651 -3.155 1.00 23.30 O ATOM 51 C3* +C B 1 -1.374 4.588 -1.383 1.00 23.40 C ATOM 52 O3* +C B 1 -2.568 3.982 -2.075 1.00 24.30 O ATOM 53 C2* +C B 1 -0.377 3.577 -0.994 1.00 23.10 C ATOM 54 O2* +C B 1 0.431 3.857 0.130 1.00 23.40 O ATOM 55 C1* +C B 1 0.368 3.469 -2.334 1.00 23.10 C ATOM 56 N1 +C B 1 1.769 3.126 -2.118 1.00 22.60 N ATOM 57 C2 +C B 1 2.012 1.742 -2.031 1.00 22.80 C ATOM 58 O2 +C B 1 1.167 0.871 -2.075 1.00 22.20 O ATOM 59 N3 +C B 1 3.367 1.447 -1.902 1.00 22.50 N ATOM 60 C4 +C B 1 4.310 2.333 -1.815 1.00 22.50 C ATOM 61 N4 +C B 1 5.559 1.913 -1.772 1.00 23.30 N ATOM 62 C5 +C B 1 3.978 3.686 -1.902 1.00 22.80 C ATOM 63 C6 +C B 1 2.757 4.028 -2.075 1.00 22.70 C ATOM 64 P G B 2 1.042 5.164 5.921 1.00 27.60 P ATOM 65 O2P G B 2 1.563 6.004 7.002 1.00 30.50 O ATOM 66 O2P G B 2 -0.332 4.837 5.921 1.00 29.80 O ATOM 67 O5* G B 2 1.482 6.299 4.797 1.00 22.30 O ATOM 68 C5* G B 2 2.658 5.942 4.149 1.00 21.00 C ATOM 69 C4* G B 2 2.892 6.875 3.025 1.00 21.20 C ATOM 70 O4* G B 2 4.265 6.766 2.853 1.00 20.70 O ATOM 71 C3* G B 2 2.362 6.641 1.686 1.00 21.30 C ATOM 72 O3* G B 2 1.706 7.839 1.167 1.00 22.30 O ATOM 73 C2* G B 2 3.538 6.439 0.778 1.00 21.30 C ATOM 74 C1* G B 2 4.732 6.486 1.599 1.00 22.10 C ATOM 75 N9 G B 2 5.325 5.179 1.772 1.00 22.50 N ATOM 76 C8 G B 2 6.708 4.962 1.902 1.00 23.10 C ATOM 77 N7 G B 2 7.013 3.655 1.988 1.00 23.50 N ATOM 78 C5 G B 2 5.765 3.017 1.902 1.00 23.50 C ATOM 79 C6 G B 2 5.442 1.649 2.031 1.00 23.40 C ATOM 80 O6 G B 2 6.214 0.747 2.161 1.00 23.50 O ATOM 81 N1 G B 2 4.059 1.369 1.902 1.00 23.50 N ATOM 82 C2 G B 2 3.188 2.349 1.686 1.00 23.30 C ATOM 83 N2 G B 2 1.904 1.991 1.513 1.00 23.70 N ATOM 84 N3 G B 2 3.475 3.655 1.686 1.00 23.40 N ATOM 85 C4 G B 2 4.759 3.951 1.815 1.00 23.30 C TER 86 G B 2 ATOM 87 P +C A 1 -6.609 -4.045 6.468 1.00 24.00 P ATOM 88 O1P +C A 1 -6.465 -3.360 5.085 1.00 21.90 O ATOM 89 O2P +C A 1 -8.172 -4.106 6.555 1.00 26.50 O ATOM 90 O5* +C A 1 -6.133 -3.158 7.722 1.00 22.80 O ATOM 91 C5* +C A 1 -5.918 -3.282 9.105 1.00 24.00 C ATOM 92 C4* +C A 1 -5.082 -2.116 9.623 1.00 23.80 C ATOM 93 O4* +C A 1 -3.916 -2.520 10.358 1.00 23.30 O ATOM 94 C3* +C A 1 -4.660 -1.104 8.586 1.00 23.40 C ATOM 95 O3* +C A 1 -4.732 0.233 9.278 1.00 24.30 O ATOM 96 C2* +C A 1 -3.286 -1.462 8.197 1.00 23.10 C ATOM 97 O2* +C A 1 -3.125 -2.302 7.073 1.00 23.40 O ATOM 98 C1* +C A 1 -2.820 -2.053 9.537 1.00 23.10 C ATOM 99 N1 +C A 1 -1.823 -3.095 9.321 1.00 22.60 N ATOM 100 C2 +C A 1 -0.503 -2.613 9.234 1.00 22.80 C ATOM 101 O2 +C A 1 -0.171 -1.446 9.278 1.00 22.20 O ATOM 102 N3 +C A 1 0.430 -3.639 9.105 1.00 22.50 N ATOM 103 C4 +C A 1 0.135 -4.899 9.018 1.00 22.50 C ATOM 104 N4 +C A 1 1.123 -5.771 8.975 1.00 23.30 N ATOM 105 C5 +C A 1 -1.203 -5.288 9.105 1.00 22.80 C ATOM 106 C6 +C A 1 -2.110 -4.402 9.278 1.00 22.70 C ATOM 107 P G A 2 -3.951 -3.484 1.282 1.00 27.60 P ATOM 108 O2P G A 2 -4.418 -4.356 0.201 1.00 30.50 O ATOM 109 O2P G A 2 -4.355 -2.131 1.282 1.00 29.80 O ATOM 110 O5* G A 2 -4.714 -4.433 2.406 1.00 22.30 O ATOM 111 C5* G A 2 -3.817 -5.273 3.054 1.00 21.00 C ATOM 112 C4* G A 2 -4.508 -5.942 4.178 1.00 21.20 C ATOM 113 O4* G A 2 -3.727 -7.077 4.350 1.00 20.70 O ATOM 114 C3* G A 2 -4.570 -5.366 5.517 1.00 21.30 C ATOM 115 O3* G A 2 -5.936 -5.397 6.036 1.00 22.30 O ATOM 116 C2* G A 2 -3.807 -6.284 6.425 1.00 21.30 C ATOM 117 C1* G A 2 -3.251 -7.341 5.604 1.00 22.10 C ATOM 118 N9 G A 2 -1.823 -7.201 5.431 1.00 22.50 N ATOM 119 C8 G A 2 -0.943 -8.290 5.301 1.00 23.10 C ATOM 120 N7 G A 2 0.341 -7.901 5.215 1.00 23.50 N ATOM 121 C5 G A 2 0.270 -6.501 5.301 1.00 23.50 C ATOM 122 C6 G A 2 1.293 -5.537 5.172 1.00 23.40 C ATOM 123 O6 G A 2 2.460 -5.755 5.042 1.00 23.50 O ATOM 124 N1 G A 2 0.844 -4.200 5.301 1.00 23.50 N ATOM 125 C2 G A 2 -0.440 -3.935 5.517 1.00 23.30 C ATOM 126 N2 G A 2 -0.772 -2.644 5.690 1.00 23.70 N ATOM 127 N3 G A 2 -1.428 -4.837 5.517 1.00 23.40 N ATOM 128 C4 G A 2 -1.042 -6.097 5.388 1.00 23.30 C TER 129 G A 2 ATOM 130 P +C A 1 6.807 -3.701 -7.938 1.00 24.00 P ATOM 131 O1P +C A 1 6.142 -3.919 -9.321 1.00 21.90 O ATOM 132 O2P +C A 1 7.642 -5.024 -7.851 1.00 26.50 O ATOM 133 O5* +C A 1 5.801 -3.732 -6.684 1.00 22.80 O ATOM 134 C5* +C A 1 5.801 -3.484 -5.301 1.00 24.00 C ATOM 135 C4* +C A 1 4.373 -3.343 -4.783 1.00 23.80 C ATOM 136 O4* +C A 1 4.140 -2.131 -4.048 1.00 23.30 O ATOM 137 C3* +C A 1 3.286 -3.484 -5.820 1.00 23.40 C ATOM 138 O3* +C A 1 2.165 -4.215 -5.128 1.00 24.30 O ATOM 139 C2* +C A 1 2.909 -2.115 -6.209 1.00 23.10 C ATOM 140 O2* +C A 1 3.556 -1.555 -7.333 1.00 23.40 O ATOM 141 C1* +C A 1 3.188 -1.416 -4.869 1.00 23.10 C ATOM 142 N1 +C A 1 3.592 -0.031 -5.085 1.00 22.60 N ATOM 143 C2 +C A 1 2.515 0.871 -5.172 1.00 22.80 C ATOM 144 O2 +C A 1 1.338 0.575 -5.128 1.00 22.20 O ATOM 145 N3 +C A 1 2.937 2.192 -5.301 1.00 22.50 N ATOM 146 C4 +C A 1 4.175 2.566 -5.388 1.00 22.50 C ATOM 147 N4 +C A 1 4.436 3.858 -5.431 1.00 23.30 N ATOM 148 C5 +C A 1 5.181 1.602 -5.301 1.00 22.80 C ATOM 149 C6 +C A 1 4.867 0.374 -5.128 1.00 22.70 C ATOM 150 P G A 2 4.993 -1.680 -13.124 1.00 27.60 P ATOM 151 O2P G A 2 5.981 -1.648 -14.205 1.00 30.50 O ATOM 152 O2P G A 2 4.023 -2.706 -13.124 1.00 29.80 O ATOM 153 O5* G A 2 6.196 -1.866 -12.000 1.00 22.30 O ATOM 154 C5* G A 2 6.475 -0.669 -11.352 1.00 21.00 C ATOM 155 C4* G A 2 7.400 -0.933 -10.228 1.00 21.20 C ATOM 156 O4* G A 2 7.992 0.311 -10.056 1.00 20.70 O ATOM 157 C3* G A 2 6.932 -1.275 -8.889 1.00 21.30 C ATOM 158 O3* G A 2 7.642 -2.442 -8.370 1.00 22.30 O ATOM 159 C2* G A 2 7.345 -0.155 -7.981 1.00 21.30 C ATOM 160 C1* G A 2 7.983 0.855 -8.802 1.00 22.10 C ATOM 161 N9 G A 2 7.148 2.022 -8.975 1.00 22.50 N ATOM 162 C8 G A 2 7.651 3.328 -9.105 1.00 23.10 C ATOM 163 N7 G A 2 6.672 4.246 -9.191 1.00 23.50 N ATOM 164 C5 G A 2 5.495 3.484 -9.105 1.00 23.50 C ATOM 165 C6 G A 2 4.149 3.888 -9.234 1.00 23.40 C ATOM 166 O6 G A 2 3.754 5.008 -9.364 1.00 23.50 O ATOM 167 N1 G A 2 3.215 2.831 -9.105 1.00 23.50 N ATOM 168 C2 G A 2 3.628 1.586 -8.889 1.00 23.30 C ATOM 169 N2 G A 2 2.676 0.653 -8.716 1.00 23.70 N ATOM 170 N3 G A 2 4.903 1.182 -8.889 1.00 23.40 N ATOM 171 C4 G A 2 5.801 2.146 -9.018 1.00 23.30 C TER 172 G A 2 ATOM 173 P +C B 1 6.807 3.701 7.938 1.00 24.00 P ATOM 174 O1P +C B 1 6.142 3.919 9.321 1.00 21.90 O ATOM 175 O2P +C B 1 7.642 5.024 7.851 1.00 26.50 O ATOM 176 O5* +C B 1 5.801 3.732 6.684 1.00 22.80 O ATOM 177 C5* +C B 1 5.801 3.484 5.301 1.00 24.00 C ATOM 178 C4* +C B 1 4.373 3.343 4.783 1.00 23.80 C ATOM 179 O4* +C B 1 4.140 2.131 4.048 1.00 23.30 O ATOM 180 C3* +C B 1 3.286 3.484 5.820 1.00 23.40 C ATOM 181 O3* +C B 1 2.165 4.215 5.128 1.00 24.30 O ATOM 182 C2* +C B 1 2.909 2.115 6.209 1.00 23.10 C ATOM 183 O2* +C B 1 3.556 1.555 7.333 1.00 23.40 O ATOM 184 C1* +C B 1 3.188 1.416 4.869 1.00 23.10 C ATOM 185 N1 +C B 1 3.592 0.031 5.085 1.00 22.60 N ATOM 186 C2 +C B 1 2.515 -0.871 5.172 1.00 22.80 C ATOM 187 O2 +C B 1 1.338 -0.575 5.128 1.00 22.20 O ATOM 188 N3 +C B 1 2.937 -2.192 5.301 1.00 22.50 N ATOM 189 C4 +C B 1 4.175 -2.566 5.388 1.00 22.50 C ATOM 190 N4 +C B 1 4.436 -3.858 5.431 1.00 23.30 N ATOM 191 C5 +C B 1 5.181 -1.602 5.301 1.00 22.80 C ATOM 192 C6 +C B 1 4.867 -0.374 5.128 1.00 22.70 C ATOM 193 P G B 2 4.993 1.680 13.124 1.00 27.60 P ATOM 194 O2P G B 2 5.981 1.648 14.205 1.00 30.50 O ATOM 195 O2P G B 2 4.023 2.706 13.124 1.00 29.80 O ATOM 196 O5* G B 2 6.196 1.866 12.000 1.00 22.30 O ATOM 197 C5* G B 2 6.475 0.669 11.352 1.00 21.00 C ATOM 198 C4* G B 2 7.400 0.933 10.228 1.00 21.20 C ATOM 199 O4* G B 2 7.992 -0.311 10.056 1.00 20.70 O ATOM 200 C3* G B 2 6.932 1.275 8.889 1.00 21.30 C ATOM 201 O3* G B 2 7.642 2.442 8.370 1.00 22.30 O ATOM 202 C2* G B 2 7.345 0.155 7.981 1.00 21.30 C ATOM 203 C1* G B 2 7.983 -0.855 8.802 1.00 22.10 C ATOM 204 N9 G B 2 7.148 -2.022 8.975 1.00 22.50 N ATOM 205 C8 G B 2 7.651 -3.328 9.105 1.00 23.10 C ATOM 206 N7 G B 2 6.672 -4.246 9.191 1.00 23.50 N ATOM 207 C5 G B 2 5.495 -3.484 9.105 1.00 23.50 C ATOM 208 C6 G B 2 4.149 -3.888 9.234 1.00 23.40 C ATOM 209 O6 G B 2 3.754 -5.008 9.364 1.00 23.50 O ATOM 210 N1 G B 2 3.215 -2.831 9.105 1.00 23.50 N ATOM 211 C2 G B 2 3.628 -1.586 8.889 1.00 23.30 C ATOM 212 N2 G B 2 2.676 -0.653 8.716 1.00 23.70 N ATOM 213 N3 G B 2 4.903 -1.182 8.889 1.00 23.40 N ATOM 214 C4 G B 2 5.801 -2.146 9.018 1.00 23.30 C TER 215 G B 2 ATOM 216 P +C B 1 -6.609 4.045 -6.468 1.00 24.00 P ATOM 217 O1P +C B 1 -6.465 3.360 -5.085 1.00 21.90 O ATOM 218 O2P +C B 1 -8.172 4.106 -6.555 1.00 26.50 O ATOM 219 O5* +C B 1 -6.133 3.158 -7.722 1.00 22.80 O ATOM 220 C5* +C B 1 -5.918 3.282 -9.105 1.00 24.00 C ATOM 221 C4* +C B 1 -5.082 2.116 -9.623 1.00 23.80 C ATOM 222 O4* +C B 1 -3.916 2.520 -10.358 1.00 23.30 O ATOM 223 C3* +C B 1 -4.660 1.104 -8.586 1.00 23.40 C ATOM 224 O3* +C B 1 -4.732 -0.233 -9.278 1.00 24.30 O ATOM 225 C2* +C B 1 -3.286 1.462 -8.197 1.00 23.10 C ATOM 226 O2* +C B 1 -3.125 2.302 -7.073 1.00 23.40 O ATOM 227 C1* +C B 1 -2.820 2.053 -9.537 1.00 23.10 C ATOM 228 N1 +C B 1 -1.823 3.095 -9.321 1.00 22.60 N ATOM 229 C2 +C B 1 -0.503 2.613 -9.234 1.00 22.80 C ATOM 230 O2 +C B 1 -0.171 1.446 -9.278 1.00 22.20 O ATOM 231 N3 +C B 1 0.430 3.639 -9.105 1.00 22.50 N ATOM 232 C4 +C B 1 0.135 4.899 -9.018 1.00 22.50 C ATOM 233 N4 +C B 1 1.123 5.771 -8.975 1.00 23.30 N ATOM 234 C5 +C B 1 -1.203 5.288 -9.105 1.00 22.80 C ATOM 235 C6 +C B 1 -2.110 4.402 -9.278 1.00 22.70 C ATOM 236 P G B 2 -3.951 3.484 -1.282 1.00 27.60 P ATOM 237 O2P G B 2 -4.418 4.356 -0.201 1.00 30.50 O ATOM 238 O2P G B 2 -4.355 2.131 -1.282 1.00 29.80 O ATOM 239 O5* G B 2 -4.714 4.433 -2.406 1.00 22.30 O ATOM 240 C5* G B 2 -3.817 5.273 -3.054 1.00 21.00 C ATOM 241 C4* G B 2 -4.508 5.942 -4.178 1.00 21.20 C ATOM 242 O4* G B 2 -3.727 7.077 -4.350 1.00 20.70 O ATOM 243 C3* G B 2 -4.570 5.366 -5.517 1.00 21.30 C ATOM 244 O3* G B 2 -5.936 5.397 -6.036 1.00 22.30 O ATOM 245 C2* G B 2 -3.807 6.284 -6.425 1.00 21.30 C ATOM 246 C1* G B 2 -3.251 7.341 -5.604 1.00 22.10 C ATOM 247 N9 G B 2 -1.823 7.201 -5.431 1.00 22.50 N ATOM 248 C8 G B 2 -0.943 8.290 -5.301 1.00 23.10 C ATOM 249 N7 G B 2 0.341 7.901 -5.215 1.00 23.50 N ATOM 250 C5 G B 2 0.270 6.501 -5.301 1.00 23.50 C ATOM 251 C6 G B 2 1.293 5.537 -5.172 1.00 23.40 C ATOM 252 O6 G B 2 2.460 5.755 -5.042 1.00 23.50 O ATOM 253 N1 G B 2 0.844 4.200 -5.301 1.00 23.50 N ATOM 254 C2 G B 2 -0.440 3.935 -5.517 1.00 23.30 C ATOM 255 N2 G B 2 -0.772 2.644 -5.690 1.00 23.70 N ATOM 256 N3 G B 2 -1.428 4.837 -5.517 1.00 23.40 N ATOM 257 C4 G B 2 -1.042 6.097 -5.388 1.00 23.30 C TER 258 G B 2 HETATM 259 O HOH A 3 -9.097 -0.669 0.951 1.00 23.50 O HETATM 260 O HOH A 4 0.054 -11.852 -2.550 1.00 26.10 O HETATM 261 O HOH A 5 -2.209 -10.825 -1.729 1.00 27.60 O HETATM 262 O HOH A 6 -2.775 6.797 1.167 1.00 30.60 O HETATM 263 O HOH A 7 -6.843 6.035 3.414 1.00 34.20 O HETATM 264 O HOH A 8 -2.335 -7.746 -0.648 1.00 35.70 O HETATM 265 O HOH A 9 -0.745 4.899 2.464 1.00 37.20 O HETATM 266 O HOH A 10 -3.906 4.868 3.025 1.00 40.40 O HETATM 267 O HOH A 11 -1.841 3.469 0.864 1.00 42.60 O HETATM 268 O HOH A 12 3.080 0.327 1.210 1.00 47.30 O HETATM 269 O HOH A 13 8.666 0.762 -3.847 1.00 51.20 O HETATM 270 O HOH A 14 -7.552 5.397 0.086 1.00 52.00 O HETATM 271 O HOH A 15 -6.717 0.529 1.297 1.00 57.20 O HETATM 272 O HOH A 16 -0.943 0.700 2.291 1.00 63.40 O HETATM 273 O HOH A 17 -5.864 3.313 2.204 1.00 64.30 O HETATM 274 O HOH A 18 -7.292 2.458 -0.346 1.00 64.40 O END